Duzela 40 mg Capsule DR contains duloxetine, an SNRI antidepressant, in a delayed-release capsule. This 40 mg strength provides an intermediate dose for individuals who require more than the initial 20 or 30 mg but are titrating up gradually. Duloxetine works by balancing levels of serotonin and norepinephrine to alleviate symptoms of major depressive disorder, generalized anxiety disorder and neuropathic pain. The delayed-release capsule ensures the medication bypasses stomach acid and is absorbed in the intestines for sustained effect and reduced gastric irritation.
Take Duzela 40mg Capsule DR exactly as prescribed by your healthcare provider. Swallow the capsule whole with water, once daily at the same time. You can take it with or without food; however, taking it with food may reduce nausea. Do not crush, chew or open the capsule. If you are switching from other antidepressants, your doctor will provide a tapering schedule to minimize withdrawal symptoms. It may take two to four weeks before you notice an improvement; continue taking it as directed even if you feel better and consult your doctor before discontinuing.
Common side effects include nausea, dry mouth, loss of appetite, dizziness, drowsiness, fatigue, increased sweating and constipation. These usually subside over time. More serious but rare effects include liver dysfunction, blood pressure changes, urinary retention, or mood changes including thoughts of self-harm. Immediately inform your doctor if you experience severe abdominal pain, dark urine, jaundice, agitation or suicidal thoughts. Duzela can interact with MAO inhibitors, SSRIs, SNRIs, St John’s Wort, triptans, tramadol, and anticoagulants, increasing the risk of serotonin syndrome or bleeding. Avoid drinking alcohol and limit caffeine. Pregnant or nursing women should use duloxetine only under medical supervision, and patients with liver disease, glaucoma or uncontrolled hypertension should not use this medication. Always inform your doctor about all medical conditions and medicines before starting Duzela 40 mg.
Take Duzela 40mg Capsule DR exactly as prescribed by your healthcare provider. Swallow the capsule whole with water, once daily at the same time. You can take it with or without food; however, taking it with food may reduce nausea. Do not crush, chew or open the capsule. If you are switching from other antidepressants, your doctor will provide a tapering schedule to minimize withdrawal symptoms. It may take two to four weeks before you notice an improvement; continue taking it as directed even if you feel better and consult your doctor before discontinuing.
Common side effects include nausea, dry mouth, loss of appetite, dizziness, drowsiness, fatigue, increased sweating and constipation. These usually subside over time. More serious but rare effects include liver dysfunction, blood pressure changes, urinary retention, or mood changes including thoughts of self-harm. Immediately inform your doctor if you experience severe abdominal pain, dark urine, jaundice, agitation or suicidal thoughts. Duzela can interact with MAO inhibitors, SSRIs, SNRIs, St John’s Wort, triptans, tramadol, and anticoagulants, increasing the risk of serotonin syndrome or bleeding. Avoid drinking alcohol and limit caffeine. Pregnant or nursing women should use duloxetine only under medical supervision, and patients with liver disease, glaucoma or uncontrolled hypertension should not use this medication. Always inform your doctor about all medical conditions and medicines before starting Duzela 40 mg.
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