Clofranil 25 mg contains clomipramine, a tricyclic antidepressant that is particularly effective in treating obsessive–compulsive disorder (OCD) and certain anxiety disorders. By inhibiting the reuptake of serotonin and norepinephrine in the brain, Clofranil 25 mg helps restore chemical balance and reduce obsessive thoughts, compulsive behaviours, and intrusive urges. The low 25‑milligram strength allows clinicians to initiate therapy at a conservative dose and titrate upward based on response and tolerance.
Beyond OCD, clomipramine is sometimes prescribed off‑label for depression, panic attacks, chronic pain syndromes and cataplexy associated with narcolepsy. It should be taken regularly as directed by a healthcare professional, typically one to three times per day with meals to reduce stomach upset. Because clomipramine has a relatively long half-life, it may take several weeks of consistent dosing before full therapeutic benefits are achieved. Patients should not abruptly stop taking the medication, as doing so can lead to withdrawal symptoms such as nausea, headache, malaise or sleep disturbances.
Common side effects of Clofranil 25 mg include dry mouth, drowsiness, constipation, blurred vision and weight gain. These reactions often diminish as the body adjusts but may persist in some individuals. More serious adverse effects can include increased heart rate, orthostatic hypotension, tremors, urinary retention, or sexual dysfunction. Seek medical attention if you experience confusion, agitation, fainting, seizures or signs of an allergic reaction. Clofranil can interact with many other medications, including SSRIs, MAO inhibitors, antihistamines and certain heart medicines, increasing the risk of serotonin syndrome or cardiac complications. It is also not recommended for individuals with uncontrolled epilepsy, heart rhythm disorders or recent myocardial infarction.
When taking Clofranil, patients should attend regular follow‑up appointments to monitor response and side effects. Because clomipramine can increase suicidal thoughts in some young adults, close observation by a caregiver is essential in the early stages of therapy. Pregnant or breastfeeding women should discuss risks and alternatives with their doctors. Used judiciously, this low‑dose tablet can be a helpful component of a comprehensive plan to manage OCD and related conditions.
Beyond OCD, clomipramine is sometimes prescribed off‑label for depression, panic attacks, chronic pain syndromes and cataplexy associated with narcolepsy. It should be taken regularly as directed by a healthcare professional, typically one to three times per day with meals to reduce stomach upset. Because clomipramine has a relatively long half-life, it may take several weeks of consistent dosing before full therapeutic benefits are achieved. Patients should not abruptly stop taking the medication, as doing so can lead to withdrawal symptoms such as nausea, headache, malaise or sleep disturbances.
Common side effects of Clofranil 25 mg include dry mouth, drowsiness, constipation, blurred vision and weight gain. These reactions often diminish as the body adjusts but may persist in some individuals. More serious adverse effects can include increased heart rate, orthostatic hypotension, tremors, urinary retention, or sexual dysfunction. Seek medical attention if you experience confusion, agitation, fainting, seizures or signs of an allergic reaction. Clofranil can interact with many other medications, including SSRIs, MAO inhibitors, antihistamines and certain heart medicines, increasing the risk of serotonin syndrome or cardiac complications. It is also not recommended for individuals with uncontrolled epilepsy, heart rhythm disorders or recent myocardial infarction.
When taking Clofranil, patients should attend regular follow‑up appointments to monitor response and side effects. Because clomipramine can increase suicidal thoughts in some young adults, close observation by a caregiver is essential in the early stages of therapy. Pregnant or breastfeeding women should discuss risks and alternatives with their doctors. Used judiciously, this low‑dose tablet can be a helpful component of a comprehensive plan to manage OCD and related conditions.
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