No, it does not affect performance because it is a mere software change in the rotation of the screen. Nevertheless, apps or games that were created earlier might appear wrong in the vertical orientation. Ensure your graphics drivers are up to date or use the default orientation in the event of a lag. Modern PCs perform rotations without problems.
For more read - https://datarecovee.com/how-to-rotate-computer-screen/
For more read - https://datarecovee.com/how-to-rotate-computer-screen/
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